Prof. Oumouna (Medea, Algerien)

CURRICULUM VITAE

Mustapha Oumouna, M.Sc. Ph.D.

Address:

Université Yahia Farès-Médéa

Faculté des Sciences et Technologies

Département Génie des Procédés

Ain Dheb, 26000 Médéa

Phone: +213- (0)25 583454/+213 (0)7 70 200 317

Email: oumouna@gmail.com

Education:

1999 Doctor of Philosophy in Biological Sciences and Fish Parasitology, University of Munich, Germany. Financée par l’Académie Allemande des Echanges Universitaires (DAAD).

1991 Magister on Biologie, Université des Sciences et Technologies Houari Boumediene

1987 D.E.S on Biologie, Université des Sciences et Technologies Houari Boumediene.

Expérience Professionnelle:

Octobre 1999-  Juin 2002: 

Postdoctoral Research Associate in Fish Molecular Immunology, Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, USA.

Aout 2002-  Juin 2004:

Postdoctoral Research Associate in Virology and Vaccine Formulations at Vaccine and Infectious Disease Organization, VIDO (University of Saskatchewan) Canada.

Juin 2004- Aout 2005:

Senior Postdoctoral Researcher at the Department of Pharmacology, School of Medicine, Louisiana State University, USA.

Janvier 2006- Mai 2007:

Maitre Assistant en Immunologie et Microbiologie: Departement des Sciences Vétérinaires et LMD.  Saad Dahled University Blida, Algeria.

Juin 2007- 2012 :

Maitre de Conférences en  Immunologie et Microbiologie: Département des Sciences Vétérinaires et LMD. Saad Dahled University Blida, Algeria.

Décembre 2012-présent :

Professeur en Immunologie : Faculté des Sciences, Université Yahia Fares, Médéa.

Special Recognition:

    1. Awarded the German Scholarship of the Exchange Services (DAAD).

2014: PrixAntoine Bechamp Award : Distinction internationale des sciences, pour les travaux de recherche dans les traitements des maladies chroniques.

Languages:  Arabic, English, French, German

Publications:

  1. ï Oumouna, M., El-Matbouli, M. and Hoffmann, R. (1996) Occurrence of actinosporean in a trout farm enzootic for Proliferative Kidney Disease (PKD). Light and electronmicroscopy (Germany). German Veterinary Medical Society 125-133.
  1. ï A. Bretzinger, T. Fischer-Scherl, M. Oumouna, R. Hoffmann and U. Truyen (1999) Mass mortalities in Koi Carp, Cyprinus carpio, associated with skin and gill disease. Bull. Eur. Ass. Fish Pathol. 19(5), 182-185.
  1. ï Oumouna, M., Mansour El-Matbouli, Rudolf W. Hoffmann and Georges Bouix (2000) Electron microscopic study of a new microsporean Microsporidium epithelialis sp. n. infecting Tubifex sp. (Oligochaete). Folia Parasitologica 47: 257-265.
  1. ï Donald Evans, Mustapha Oumouna & Liliana Jaso-Friedmann (2000) Nonradiometric detection of cytotoxicity of teleost nonspecific cytotoxic cells. Methods in Cell Science. 22: 233-237.
  1. ï M. Oumouna, L. Jaso-Friedmann and D.L. Evans (2001) A Flow Cytometry Assay for Determination of Teleost Cytotoxic Cell Lysis of Target Cells. Cytometry 45: 259-266.
  1. ï M. Oumouna, M. El-Matbouli, R.W. Hoffmann and S.L. Hallett (2002) Early developmental stages of two actinosporeans, Raabeia and Aurantiactinomyxon (Myxozoa), as detected by light and electron microscopy. Journal of Invertebrate Pathology 79: 17-26.
  1. ï M. Oumouna, L. Jaso-Friedmann and D.L. Evans (2002) Activation of Cytotoxic Cells (NCC) with Synthetic Oligonucleotides and Bacterial Genomic DNA: Binding, Specificity and Identification of Unique Immunostimulatory Motifs. Developmental and Comparative Immunology 26: 257-269.
  1. ï M. Oumouna, S. L. Hallett, R. W. Hoffmann, and M. El-Matbouli (2003) Seasonal occurrence of actinosporeans (Myxozoa) and oligochaetes (Annelida) from a Trout hatchery in Bavaria, Germany. Parasitology Research 89: 170-189.
  1. ï M. Oumouna, J. Mapeltoft, B. Karvonen, L. Babiuk and S. van Den Hurk (2005). Effects of CpG oligonucleotides (ODN) adjuvants on immune responses and protection induced by bovine respiratory syncytial virus (BRSV) formalin inactivated (FI) or commercial killed vaccines (K-BRSV). Journal of Virology 79: 2024-2032. ISSN: 0022538.
  1. ï John W. Mapletoft, Mustapha Oumouna, Hugh G. Townsend, Lorne A. Babiuk, Sylvia van Drunen Little-van den Hurk. (2005). Formulation with CpG oligodeoxynucleotides increases cellular immunity induced by vaccination with formalin-inactivated bovine respiratory syncytial virus. Virology 353:316-23.
  1. ï Boulares H, Zoltoski A, Kandan S, Akbulut T, Yakovlev A, Oumouna M (2006) Correlation between decreased sensitivity of the Daudi lymphoma Cell to VP-16-induced apoptosis and deficiency in DNAS1L3 expression. Bichem Biophys Res Commun 341: 653-662.

 

  1. ï Oumouna Mustapha, Rahul Datta, Karine Oumouna-Benachour, Yasuhiro Suzuki, Kametra Matthews, Kenneth Fallon and A. Hamid Boulares (2006). Poly(ADP-ribose) Polymerase-1 Inhibition Prevents Eosinophil Recruitment by Modulating Th2 Cytokines in a Murine Model of Allergic Airway Inflammation: A Potential Specific Effect on IL-5. Journal of Immunology 177: 6489-6496.
  1. ï Karine Oumouna-Benachour, Mustapha Oumouna, Mourad Zerfaoui, Chetan Hans, Kenneth Fallon, A. Hamid Boulares (2007). Intrinsic resistance to apoptosis of colon epithelial cells is a potential determining factor in the susceptibility of the A/J mouse strain to dimethylhydrazine-induced colon tumorigenesis. Molecular carcenogenesis 115: 2442-2450. ISSN: 1098-2744.
  1. ï John W. Mapletoft, Mustapha Oumouna, Jennifer Kovacs-Nolan, Laura Latimer, George Mutwiri, Lorne A. Babiuk, and Sylvia van Drunen Littel-van den Hurk (2008). Intranasal immunization of mice with a formalin-inactivated. bovine respiratory syncytial virus vaccine co-formulated with CpG oligodeoxynucleotides and polyphosphazenes results in enhanced protection. Journal of General Virology 89: 250-260. ISSN: 0022-1317. 
  1. ï Naura AS, Hans CP, Zerfaoui M, You D, Cormier SA, Oumouna M, Boulares AH (2008). Post-allergen Challenge Inhibition of Poly(ADP-ribose) Polymerase Harbors Therapeutic Potential for treatment of Allergic Airway Inflammation. Clinical and Experimental Allergy 38: 839-846. ISSN: 1365-2222.
  1. ï  Naura AS, Datta R, Hans CP, Zerfaoui M, Rezk BM, Errami Y, Oumouna M, Matrougui K, Boulares H (2009). Reciprocal regulation of iNOS and PARP-1 during allergen-induced eosinophilia. European Respiratory Journal 33: 252-262. ISSN: 0903-1936.
  1. Rahal K., Guedioura M. et Oumouna M (2009) Paramètres morphométriques du cheval barbe de Chaouchaoua. Revue Méditerranéenne Vétérinaire 12 : 586-589.
  1. ï Van den Broeke A, Oumouna M, Beskorwayne T, Szynal M, Cleuter Y, Babiuk S, Bagnis C, Martiat P, Burny A and Griebel P (2010). DNA Vaccination Induces Tax-Specific Cytotoxic Cells, Alters Bovine Leukemia Virus Replication but Does not Prevent Oncogenesis. Leukemia Research 34: 1663-1669. ISSN: 0145-2126.
  1. Rahul Datta, Amarjit S. Naura, Mourad Zerfaoui, Mustapha Oumouna, Hogyoung Kim, Jihang Ju, Youssef Errami, and A. Hamid Boulares (2011). PARP-1 deficiency blocks IL-5 expression through calpain-dependent degradation of STAT-6 in a murine asthma model. Allergy 7: 853-861. ISSN:1398-9995.
  1. Mokrani D, Bendedouche B and Oumouna M (2012) Correlation between the sensory and chemical indicators used for assessing the freshness of the sardine (Sardina pilchardus). International Research Journal of Basic and Applied Science 4: 23-28. ISSN:2077-1223.
  1. Chebaani N, Guardiola FA, Sihem M, Nabil A, Oumouna M, Meseguer J, Esteban MA, Cuesta A (2014). Innate humoral immune parameters in Tilapia zillii under acute stress by low temperature and crowding. Fish Physiol Biochem. 40(3):797-804.
  1. Errami Y, Brim H, Oumouna-Benachour K, Oumouna M, Naura AS, Kim H, Ju J, Davis CJ, Kim JG, Ashktorab H, Fallon K, Xu M, Zhang J, Del Valle L, Boulares AH (2013). ICAD deficiency in human colon cancer and predisposition to colon tumorigenesis: linkage to apoptosis resistance and genomic instability. PLoS One.;8(2):57871.
  1. Mustapha Oumouna, Michael Weitnauer, Vedrana Mijosek, Lotte M.Schmidt, Alexander H. Dalpke (2015) Cell-contact dependent inhibition of monocytes by airway epithelial cells and reversion by infection with Respiratory Syncytial Virus. Immunobiology. 2015 220(11):1240-1245.

Oral Presentations;

ï Oumouna, M. and Benmeradi, N. (1990) Preliminary results about the reproduction cycle of Sepia officinalis L. 1st. Maghrebin Meeting of Marine Science. Algeria, Sidi-Fredj, 3-5 May.

ï Benmeradi, N. and Oumouna, M. (1990) Influence of diet on the growth of mussel larvae, Perna perna L. 1st. Maghrebin Meeting of Marine Science. Algeria, Sidi-Fredj, 3-5 May.

ï Oumouna, M. and Benmeradi, N. (1993) Structural and ultrastructural evolution of the accessory nidamentale glands during the reproduction cycle of Sepia officinalis L. Annual Meeting of the French Society of Zoology. France, Bordeaux 5-7 July.

ï Oumouna, M., El-Matbouli, M. and Hoffmann, R. (1996) Occurrence of actinosporean in a trout farm enzootic for Proliferative Kidney Disease (PKD). Meeting of the German Veterinary Medical Society and the German Section of the European Association of Fish Pathologists (EAFP). Germany, Königswartha, 24-26 September.

ï Oumouna, M., El-Matbouli, M. and Hoffmann, R. (1999) Actinosporeans in a trout farm for Proliferative Kidney Disease (PKD). V International Symposium of Fish Parasites. Czech republic, Ceske Budejovice 9-13 August.

ï Oumouna, M., Friedmann-Jaso, L. and Evans, DL. (2002) Binding of Bacterial Genomic DNA and Synthetic Oligonucleotides leads to Activation of Tilapia Nonspecific Cells (NCC). 27th Eastern Fish Health Workshop, USA, South Carolina, 18-22 March.

ï Oumouna, M., J. Mapeltoft, B. Karvonen, L. Babiuk and S. van Den Hurk (2004). Effects of CpG oligonucleotides (ODN) adjuvants on immune responses and protection induced by bovine respiratory syncytial virus (BRSV) formalin inactivated (FI) or commercial killed vaccines (K-BRSV). 23rd Annual Meeting of American Society for Virology. Canada, Montreal, 10-14 July.

Abstract Presentations:

ï Oumouna, M., El-Matbouli, M. and Hoffmann, R. (1995) Occurrence of Actinosporea in trout farm with a long history of Proliferative Kidney Disease (PKD). VI International Symposium of Fish Parasitology. Germany, Munich 3-7 October.

ï M. Oumouna, L. Jaso-Friedmann, H. Kaur and D. L. Evans (2001) Mechanisms of Innate Immunity in Teleost: Activation of Cytotoxicity with Bacterial DNA and Synthetic Oligodeoxynucleotides. Annual Meeting of the American Association of Immunologists (2001). USA, Orlando, Florida, March31-April 4.

ï H. Kaur, M. Oumouna, L. Jaso-Friedmann and D. L. Evans (2001) Role of Bacterial DNA and Oligonucleotides Motifs in Innate Immune Defense Mechanisms in Fish. Veterinary Research Day. USA, Athens, Georgia, February 12th.

ï D. L. Evans, M. Oumouna, Harjeet Kaur and L. Jaso-Friedman (2001) Activation of Nonspecific Cytotoxic Cells (NCC) by Novel Immunostimulatory Oligodeoxynucleotides. The 5th Nordic Symposium on Fish Immunolog. Norway, Sundvolden, 18-22 June.

ï D. L. Evans, M. Oumouna, and L. Jaso-Friedman (2002) In Vivo Activation of Nonspecific Cytotoxic Cells (NCC) with Oligodeoxynucleotides and Bacterial Genomic DNA. Annual Meeting of the American Association of Immunologists. USA, Orleans, Louisiana, April 19- 23.

ï Hamid Boulares, Yasuhiro Suzuki, Amarjit Naura, Mustapha Oumouna, Rahul Datta, and Chetan Hans (2007). PARP-1 and iNOS relationship in allergen-induced lung inflammation: dependence of iNOS expression on PARP-1 and its dispensability for eosinophil recruitment post-IL-5 production. American Association of immunologists, Miami Beach, Florida, USA, May 18-22.

ï Mustapha Oumouna, Kametra M. Matthews, Kirk Hutchinson, Rahoul Datta, Kenneth Fallon and Hamid Boulares (2005) Role of PARP-1 in Th2-cytokine secretion and mucus production in a murine model of asthma. Experimental Biology Meeting, USA, San Diego, California, April 2-6.

ï John W. Mapletoft, Mustapha Oumouna, Hugh G. Townsend, Lorne A. Babiuk, Sylvia van Drunen Little-van den Hurk (2005) Formulation with CpG oligodeoxynucleotides increases cellular immunity induced by vaccination with formalin-inactivated bovine respiratory syncytial virus. Vaccine Congress, Germany, Berlin, September 8-10. 

ï Amarjit Singh Naura, Mustapha Oumouna, Mourad Zerfaoui, Chetan Hans, Yasuhiro Suzuki, and Hamid Boulares (2007) A post-allergen challenge inhibition of PARP prevents airway eosinophilia and reduces Th2 cytokines and mucus production in animal model of asthma:

a clinical potential in the treatment of asthma. American Association of immunologists, Miami Beach, Florida, USA, May 18-22.

ï Hamid Boulares , Yasuhiro Suzuki , Amarjit Naura, Mustapha Oumouna, Rahul Datta and Chetan Hans (2007). PARP-1 and iNOS relationship in allergen-induced lung inflammation: dependence of iNOS expression on PARP-1 and its dispensability for eosinophil recruitment post-IL-5 production.

ï Amarjit Singh Naura, Mustapha Oumouna, Mourad Zerfaoui, Chetan Hans, Yasuhiro Suzuki and Hamid Boulares (2007). A post-allergen challenge inhibition of PARP prevents airway eosinophilia and reduces Th2 cytokines and mucus production in animal model of asthma: a clinical potential in the treatment of asthma.

. Oumouna Mustapha, Dalpke Alexander (2014). RSV infection revert the inhibitory effects of bronchial epithelial cells on monocytes. The 9th International Respiratory Syntial Virus Symposium. 9 – 13 November at the Spier Hotel & Conference Centre, Stellenbosch, South Africa.